Neural Mechanisms of Pain Modulation
Principal Investigators:
Contact Information:
Email: morgan@vancouver.wsu.edu
Office: VANC CL 208V (Vancouver Campus)
Phone: (360) 546-9726
Website:
Lab websiteSummary:
The analgesic effects of morphine and other opioids decrease with repeated administration. Our lab has shown that a brain structure known as the periaqueductal gray plays an important role in morphine analgesia and tolerance. Our current objective is to understand the neural mechanism within the periaqueductal gray that causes this change in morphine potency. These studies use in vitro electrophysiology and behavioral pharmacology to link molecular changes in cell signaling to behavior.