Introduction to Population Genetics (BIOL 519/GENE 505)
Fall 2016
Dr. Richard Gomulkiewicz

Meeting	Date	Topics covered	Outline pages	Materials
1	Aug. 23	Introduction Hardy-Weinberg world Asexual inheritance	I-1 to I-2	Syllabus (see below for updated version) Sample Critique Notes I-1 to I-7 Fun Facts about discrete random variables and logs
2	Aug. 25	Haploid, Diploid, Polyploid Hardy-Weinberg	I-2 to I-5	Handouts I.1 & I.2
3	Aug. 30	Sex differences Sex linkage Multilocus genotypes Linkage disequilibrium	I-6 to I-10	Handout I.3 Notes I-8 to I-11
4	Sep. 1	Recombination Interpreting D	I-10 to I-11	Handout I.4 Notes I-12 to I-16
5	Sep. 6	Estimation Likelihood Hypothesis testing	I-12 to I-15	Homework 1 Notes II-1 to II-6
6	Sep. 8	Likelihood ratio test Nonrandom mating Mini-discussion 1: Nielson & Slatkin pp. 116-118 & problems 6.5 on p. 127 & 6.7 on p. 128	I-15 to I-16 & II-1	Handout II.1 Notes II-7 to II-9 Handout II.2
7	Sep. 13	The Wahlund Effect Inbreeding	II-1 to II-4	Drift Handout Handout II.3 Notes II-10 to II-16 Notes II-17 to II-22 Notes II-23 to II-28
8	Sep. 15	Computing inbreeding coefficients F Statistics	II-4 to II-9
9	Sep. 20	Homework 1 due Genetic Drift	II-9 to II-12	Notes III-1 to III-4
10	Sep. 22	Wright-Fisher Model	II-12 to II-14
11	Sep. 27	Bottlenecks Mutation Mutation vs drift: infinite alleles model	II-14 to II-21	Homework 2 Updated Syllabus Homework 1 Key
12	Sep. 29	Effective numer of alleles Neutral substitution rate The coalescent	II-21 to II-25
13	Oct. 4	The coalescent	II-25 to II-27
14	Oct. 6	Effective population size Mini-discussion 2: Nielson & Slatkin pp. 42-43 & 53-56 & problems 3.5-3.8 on p. 58	II-27 to II-28	Notes IV-1 to IV-3
15	Oct. 11	Migration	III-1 to III-4	Notes IV-4 to IV-7 Notes IV-8 to IV-12
16	Oct. 13	Homework 2 due Selection	III-4 & IV-1 to IV-2	Notes IV-13 to IV-17 Notes IV-A to IV-B
17	Oct. 18	Absolute & relative fitness Selection coefficients Diploid selection	IV-2 to IV-4
18	Oct. 20	Dominance Selective spread	IV-4 to IV-7	Selection Handout
19	Oct. 25	Over- & under-dominance	IV-8 to IV-10	Homework 2 Key Homework 3
20	Oct. 27	Analyzing stability Multilocus selection	IV-10 to IV-12 & IV-A
21	Nov. 1	Hitchhiking Genetic draft Wright's adaptive topography Mini-discussion 3: Nielson & Slatkin pp. 205-208	IV-A to IV-B & IV-13	Excel Demo Notes IV-18 to IV-21 Notes IV-22 to IV-24 Notes IV-25 to IV-27
22	Nov. 3	Fisher's fundamental theorem Simulating selection	IV-14 to IV-20	Last day for approval of presentation topic
23	Nov. 8	Homework 3 due Mutation & selection Mutational load	IV-20 to IV-24	Notes for inbreeding depression
24	Nov. 10	Inbreeding & selection Inbreeding depression Selection & drift	Inbreeding depression, IV-25	Notes IV-28 to IV-33 Selection & Drift Handout
25	Nov. 15	Selection & drift Selection, drift, and mutation Selection & migration		Notes V-1 to V-4 Homework 3 Key
26	Nov. 17	A taste of quantitative genetics Mini-discussion 4: Leffler et al. 2012. PLoS Biology 10:e1001388		Leffler et al. reading Homework 4
	Nov. 22	Thanksgiving Break
	Nov. 24	Thanksgiving Break
27	Nov. 29	PRESENTATIONS Elizabeth Keuter Lea Flechon & Josh Wemmer Andy Horgan & Jacob Lamkey Kelcey McBride		Presentation Summary Sheets: Keuter Wemmer & Flechon McBride Lamkey & Horgan
28	Dec. 1	PRESENTATIONS Danielle Guzman & Bruce Williamson Benavides Alexander Olson Galen Miller-Atkins Carlie Harding & Joel Nelson		Presentation Summary Sheets: Miller-Atkins Guzman & Williamson Harding & Nelson
29	Dec. 6	PRESENTATIONS Stephanie Sjoberg, Dylan Larkin, & Nikayla Strauss Megan Asche & Kelly Sears Lederson Ganan Joseph Kleinkopf		Presentation Summary Sheets: Kleinkopf Asche & Sears Ganan Sjoberg, Strauss, & Larkin
30	Dec. 8	PRESENTATIONS Presentation Summary Sheets due Seminar Synopses due Homework 4 due Ian Gilman, Amanda Stahlke, & Bob Week Travis Ruff & Shelby Westenskow Julianne Kellogg & Leo Hinojosa		Presentation Summary Sheets: Gilman, Stahlke, & Week Kellogg & Hinojosa Ruff & Westenskow

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