..Last updated:
..Oct. 12 , 2009

The Lange laboratory investigates pathways leading to natural products (with an emphasis on terpenoids) using functional genomics and systems biology approaches. We study plant metabolism as an interacting network of biochemical reactions by taking advantage of recent and continuing advances in analytical chemistry and computational biology. We are developing mathematical models to quantitatively describe the regulation of metabolic pathways, thus enabling knowledge-based approaches for pathway improvements by metabolic engineering.

Contact Mark Lange at lange-m@wsu.edu .

Lange Laboratory News:

2009 (Aug./Sept.)

Dan Cuthbertson and Mark Lange present posters at the 5th International Conference of the Metabolomics Society (WebLink).

2009 (May)

Lange laboratory research on modifying peppermint essential oil is featured in an article published by the Capital Press, an agricultural newspaper based in Salem, OR (WebLink).

2009 (April)

Cindy Meyrat graduates with a diploma (masters) degree in Analytical Chemistry from the University of Applied Sciences in Sion, Switzerland (WebLink). Her thesis work, which involves the development of CE-MS methods for profiling various anionic metabolites, has been performed in the Lange laboratory.

2009 (March)

Dan Cuthbertson and Max Feldman present posters at WSU's Academic Showcase (WebLink).

2009 (March)

Mark Lange gives an invited talk as part of the seminar series of the Department of Cell and Systems Biology at the University of Toronto, ON (WebLink).

2009 (March)

Mark Lange gives an invited talk as part of the seminar series of the Department of Chemistry at Washington State University (WebLink).

2009 (January)

Mark Lange gives an invited talk at the Annual Convention of the Mint Industry Research Council (Lahaina, Hawaii) (WebLink).

2008 (December)

Rigoberto Rios-Estepa graduates with a Ph.D. degree in Chemical Engineering. The emphasis of his thesis is the development and experimental testing of mathematical models of peppermint essential oil biosynthesis. He is now working as an Assitant Professor at the University of Antioquia in Colombia (WebLink).

2008 (November)

Mark Lange gives an invited talk as part of the seminar series of the Biochemistry Division at the University of Missouri, Columbia (WebLink).

2008 (September)

Caroline Emery receives the Dr. Max Lüthi Award (WebLink) from the Swiss Chemical Society for her outstanding diploma (masters) thesis. She is now working as an Analytical Chemist at the Swiss Laboratory for Doping Analyses in Lausanne (WebLink).

2008 (September)

Mark Lange gives an invited talk at the Metabolic Engineering VII Conference in Puerto Vallarta, Mexico (WebLink).

2008 (July-September)

Dan Cuthbertson works for three months as an internship student with Dr. Steve Fisher at the Agilent Metabolomics lab (WebLink). He is involved in the development of a compound library for LC-MS.

2008 (August)

Mark Lange gives an invited talk as part of the seminar series of the Genetics Department at Iowa State University (WebLink).

2008 (July)

Blake Herron completes his Undergraduate Honors Thesis at WSU. His work in the Lange laboratory focuses on investigating the regulation of sterol biosynthesis in Arabidopsis.

2008 (June)

Rigoberto Rios-Estepa gives an oral presentation at the Annual Meeting of the Phytochemical Society of North America (WebLink).

2008 (June)

Majid Ghassemian, former postdoctoral associate in the Lange laboratory at the Torrey Mesa Research Institute, is appointed Director of the Biomolecular Mass Spectrometry Facility at UC San Diego (WebLink).

2008 (January)

Rigoberto Rios-Estepa receives a Loyal Davis Fellowship from the Institute of Biological Chemistry at WSU for excellent progress during his doctoral thesis.

2008 (January)

Lange laboratory research on modifying peppermint essential oil is featured in an article published by the Capital Press, an agricultural newspaper based in Salem, OR (WebLink).

2008 (Jan.)/2007 (Dec.)

Mark Lange gives invited talks at the Annual Conventions of the mint commissions of Washington, Oregon and Idaho.

2007 (November)

Mark Lange gives an invited talk as part of the seminar series of the Samuel Roberts Noble Foundation in Ardmore, Oklahoma (WebLink).

2007 (July)

Mark Lange receives the Arthur C. Neish Young Investigator Award of the Phytochemical Society of North America (WebLink).

2007 (July)

Rigoberto Rios-Estepa receives the Best Student Poster Award at the Annual Meeting of the Phytochemical Society of North America (WebLink).

2007 (July)

Mark Lange gives an invited talk at the Annual Meeting of the Phytochemical Society of North America (WebLink).

2007 (March)

Caroline Emery graduates with a diploma (masters) degree in Analytical Chemistry from the University of Applied Sciences in Sion, Switzerland (WebLink). Her thesis work, which involves the development of an LC-MS method for profiling sugar phosphates using mixed-mode stationary phases, has been performed in the Lange laboratory.

2007 (March)

Julie Ann Bick, former postdoctoral associate in the Lange laboratory at the Torrey Mesa Research Institute, is appointed Executive Vice President and Chief Scientific Officer at Cellexus Biosystems (WebLink).

2007 (July)

Mark Lange gives an invited talk at the Annual Meeting of the Canadian Society of Plant Physiology (WebLink).