If Ethel is the mother of the child, which is the more likely father, Fred or Joe? Justify your answer. (Assume that all the variation in these individuals is related to variation in the number of repeats).
Individual |
Allele detected |
Band size after PCR |
Fred |
1 |
500 |
Fred |
2 |
800 |
Ethel |
1 |
550 |
Ethel |
2 |
600 |
Joe |
1 |
600 |
Joe |
2 |
700 |
Ethels child Alleles detected: 500 and 600 bp.
Fred is the most likely father. The child must have gotten one allele from the mother (Ethel) and it must have been the 600 bp allele because the 550 bp allele is not present in the child. The other allele in the child,500 bp, is present in Fred but not in Joe.
2. Using the genetic code table below, list the possible single base substitution mutations that could take place from a GGA (glycine) codon, and which are silent, missense and nonsense mutations.
Possible single base substitutions:
UGA stop codon nonsense
CGA arg missense
AGA arg missense
GUA val missense
GCA ala missense
GAA glu missense
GGU gly silent
GGC gly silent
GGG gly silent